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Through controlling these targets, HSF1 acts in diverse stress-induced cellular processes and molecular mechanisms, including the endoplasmic reticulum unfolded protein response and ubiquitinproteasome system, multidrug resistance, autophagy, apoptosis, immune response, cell growth arrest, differentiation underlying developmental diapause, chromatin remodelling, cancer development, and ageing

Nano silver cannot be easily inactivated due to its particulate properties, and its controlled release also makes it unnecessary to use a large dose at one time

Moreover, the appearance of both HuR cleavage products and higher-molecular weight species in the absence of caspase-3 activation suggests that HuR undergoes caspase-independent modification during APAP-induced hepatotoxicity, consistent with the predominance of necrotic cell death in this model

Deep phenotyping of myalgic encephalomyelitis/chronic fatigue syndrome in Japanese population