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The following parameters were used: carbamidomethylation as a fixed modification, protein N -acetylation and methionine oxidation as variable modifications, a first search error window of 20 ppm, and a main search error of 4.5 ppm

(1997) 273:G717

In rats, gavage of trimetazidine (10 mg/kg/day) for 7 days prior to induction of acute myocardial ischemia preserved the mitochondrial structure, improved respiratory control ratio and mitochondrial complex I activity, as well as mitochondrial biosynthesis and fusion [137]

In view of the above, if a way could be found to elevate circulating and intracellular levels of glutathione, this would offer an interventional approach to overcome disease-mediated deficiencies in intracellular glutathione levels