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These mechanisms are reported in available scientific literature and are presented for informational purposes only, within a research context

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Furthermore, inhibitory potentials of IKK are associated with in various diseases through regulating the NF-B pathway, including cancer, PD, diabetes, SCI, NAFLD, osteolysis, and arthritis, therefore, it has been considered a potential target

6.6.4 Glucocorticoids The presence of glucocorticoid receptors in endothelial and inflammatory cells (240243), as well as increased concentrations of circulating glucocorticoids at the onset of inflammation downregulating inflammatory responses, is proof that glucocorticoids are modulators of inflammatory responses (243, 277)