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By Day 45, reduced CYP expression correlated with the emergence of mesenchymal-like cells, although functional hepatocytes remained, as evidenced by continued ALB localization in immunostaining analyses

Metabolic Research Lipolysis and Fat Metabolism Animal studies have investigated the metabolic effects of enhanced growth hormone secretion: Growth hormone-mediated lipolysis through hormone-sensitive lipase activation Increased free fatty acid availability for energy utilization Preferential reduction of visceral adipose tissue in preclinical models Improved insulin sensitivity markers in some experimental conditions Research suggests growth hormone elevations enhance lipid oxidation while preserving lean tissue during energy restriction