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This project has received funding from the Horizon Europeans research and innovation programme HORIZON-HLTH-2022-STAYHLTH-02 under agreement [101095679]

Nrf2 is a critical modulator of this process

They also included the coupling helices ICL5 and ICL7 and their associated TMs 10-11 and 14-15, respectively, due to their role in substrate transport 34,35