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SKU: 74412199697
Price: 24.67 USD
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Description

C.SetlowB.SetlowP

Comparison of GT2 domains with and without donor substrates highlighted a conformational rearrangement of the otherwise flexible C-terminus of the domain for residues 562580, wrapping around the donor substrate binding cavity and positioning the backbone carbonyl of residue Ser569 and Thr571 in a productive conformation for hydrogen bonding with both phosphates of the UDP donor substrate (Fig