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Future studies should investigate the molecular mechanisms of signalling at MERCs to contribute to the understanding of how the MITOLHMOX2 pathway responds to mitochondrial iron demand

We additionally confirmed the RTA activity of VKH 2 reduced chemically or by FSP1-mediated reaction using LipiRADICALGreen (previously called NBD-Pen 26,27 ), a fluorescence probe for lipid-derived radicals (Extended Data Fig