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This suggests that C32E8.9 plays a role in modulating transcriptome alterations induced by mrps-5 RNAi, as the transcriptome of the double knockdown demonstrates a shift towards the control on the first principal component compared to the effects of mrps-5 RNAi alone

Immunology 144 , 7990 (2015)

148 Within phagosomes, two pivotal cytotoxic mechanisms are initiated: (1) the generation of reactive oxygen species (ROS) via nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and (2) the release of bactericidal proteins from preformed granules, namely oxidative and non-oxidative killing