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As an example, we described in the case of Leqembi (lecanemab-irmb), a drug targeting cerebral amyloid-beta plaques in Alzheimer's disease to receive FDA approval, the first date of sale reported to CMS via the Average Sales Price (ASP) portal was in January 2023, as it was marketed and sold under accelerated approval granted on January 6, 2023

Under both arrangements, the NGACO was responsible for 100 percent of performance year expenditures for services rendered to the NGACO's aligned beneficiaries

No medical claims.

However, irrespective of whether ASV abundance was weighted in the analysis, beta diversity analyses revealed distinct clustering by treatment group