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doi: 10.1210/jc.2007-2350 47 HedmanCAFrystykJLindstromTChenJWFlyvbjergAOrskovHet al

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Key findings include: High daily doses (48 IU) showed beneficial effects on social impairments Lower doses showed no significant difference from placebo Chronic administration may stimulate endogenous oxytocin production Individual variation in response suggests genetic or baseline differences in oxytocin systems A 2024 study found that chronic intranasal oxytocin administration in children with autism stimulated their own oxytocinergic system, suggesting potential for lasting benefits beyond the treatment period