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There was also some concern as to whether the metallurgy of existing chiller systems is sufficiently robust to withstand what could be a somewhat more harsh environment [from the effluent], says Hodgson

The ATP synthase beta subunit, a mitochondrial enzyme involved in redox regulation, associates with FUS, inducing the mitochondrial UPR in cellular and transgenic Drosophila models of ALS (Deng et al., 2018)

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4.5.4.1 Study design constraints and causality Most metabolomic studies linking uremic toxins (IS, pCS, PAGln) and BCAAs to DKD employ cross-sectional or case-control designs