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Brand: eipa.cz
SKU: 76520777310
Price: 29.15 USD
Availability: InStock
Rating: 4.4248 (23 reviews)

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SKU: 76520777310 · From eipa.cz

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Description

Originally identified in a screen for compounds selectively lethal to RAS-mutant cancer cells, RSL3 triggers ferroptotic cell death by inactivating GPX4, leading to the accumulation of toxic amounts of reactive oxygen species (ROS) and subsequent oxidative membrane damage [1]