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Delayed effects on subsequent night sleep were shorter sleep onset, reduced percentage of stage 1, and better sleep efficiency The results suggest that DSIP in humans is also efficacious by sustaining natural sleep functions

For example, IL-1 promotes BMSC migration via the NF-B pathway but inhibits their chondrogenic differentiationan effect that can be alleviated under hypoxic conditions (Teixeira et al., 2018)