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Description

Cerebral Folate Deficiency Syndrome: Early Diagnosis, Intervention and Treatment Strategies

10.1016/j.freeradbiomed.2021.08.234 385 SakakiS.KuwabaraH.OhtaS

Total symptom score decreased significantly compared to placebo across treatment groups of all doses 600-1800 mg/d oral ALA, yet there was a dose-dependent increase in nausea, vomiting, and vertigo, and therefore the lowest dose of oral ALA (600 mg/d) is recommended