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Isolated animals have alterations in striatal dopamine function, abnormalities in the hippocampus and frontal cortex, and abnormal firing of pyramidal cells in the prefrontal cortex [53]

GCL activity may be mildly to moderately reduced, so glutathione synthesis can be a bit less efficient than in people without the variant

In contrast with this hypothesis, numerous studies investigating the biological effects of these nutrient supplementations did not support their positive association with CVD [50], suggesting that the relationship between nutritional intake of choline and l-carnitine and CVD could be more complex than as initially hypothesized

Figure 5 Figure 6 cis-Elements in the Promoter Regions of SlUGT Genes To study the regulatory mechanism of the SlUGT gene, the sequence of the promoter codon 2000 bp upstream of (ATG) was scanned in the PlantCARE database, and a variety of cis-acting elements related to plant hormones and stress responses were obtained (Figure 7)