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The impact of the intervention was determined by measuring the resulting erythrocyte and leucocyte glutathione concentrations, and biomarkers of oxidative stress

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The experimental results showed decreased levels of intracellular cyclic adenosine monophosphate (cAMP) and inhibition of cAMP-responsive element-binding protein (CREB) phosphorylation [137]

Powders and capsules containing goldenseal (which naturally contains berberine) were particularly likely to have issues