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Infected erythrocytes undergo oxidative stress, which in turn causes activation of calcium-dependent cation channels and facilitates Ca 2+ entry into the erythrocyte

Drugs based on siRNA, miR, mRNA, lncRNA, zinc fingers, and CRISPR-Cas proteins have joined traditional small molecule therapies, where each drug class will bring multiple options [139] as the biological response to NPs loaded with nucleic acids differs from those loaded with RNA