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Description

Catalase deficiency is linked with many diseases, such as neurological disorders (Alzheimers disease, Parkinsons disease, schizophrenia, and bipolar disorder), metabolic diseases (diabetes I and II, hypertension, insulin resistance), and cancer, anemia, and asthma

10.1371/journal.pone.0143344 PLoS One 29 JanaG

NOX2 activity promotes ET-1 production in ECs [49], and NOX-mediated superoxide production contributes to ET-1-dependent regulation of vascular homeostasis in physiology and disease [90]

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