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Follicular atresia caused by GC apoptosis is the primary process responsible for the loss of follicles and oocytes in the mammalian ovary and is one of the pathogenic mechanisms of premature ovarian failure (Krysko et al., 2008

The AsA/DHA ratio increased significantly (1.2~2 times) under hyposaline stress, mainly due to the decrease of DHA content

Vitamin D may also act through VDR to lower microbial dysbiosis and improve intestinal barrier function with a rise in SCFA production by commensal bacteria

As noted above, Trxs are responsible for reducing Prx back to their reduced, oxidant-scavenging state, while thioredoxin reductases (TrxRDs) keep the reduced state of Trxs using NAPDH reducing equivalents, as depicted in Figure 2