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Description

Profiling the carbonylome in CF provides a molecular fingerprint of irreversible oxidative damage, revealing vulnerable cellular pathways and potential therapeutic targets (Starosta et al., 2006)

The cobalamin enters the bloodstream directly and is available to tissues within hours

PMID: 21708034

The lowest level denotes impaired mitochondrial features (static molecular components), such as altered mitochondrial shape and size, as well as damage to cristae and mitochondrial DNA (mtDNA)