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[DOI] [PubMed] [Google Scholar] 57.Langbein H., Brunssen C., Hofmann A., Cimalla P., Brux M., Bornstein S.R., Deussen A., Koch E., Morawietz H

However, chronic excessive alcohol consumption leads to significant metabolic disruptions: (1) Disruption of the NADH/NAD + Ratio: This imbalance enhances respiratory chain activity, increases oxygen consumption, and promotes ROS formation (Yang et al., 2022)

2.3.2 Dysfunction of innate immune cells in MS Innate immune cells within the CNS are key drivers and modulators of damage in MS

Immunization to rituximab is more frequent in systemic autoimmune diseases than in rheumatoid arthritis: ofatumumab as alternative therapy