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Multiple randomised trials from the 1970s and 1980s have shown its antiparkinsonian efficacy while its antidyskinetic efficacy in PD patients with LIDs was only demonstrated some 30 years after its introduction into PD therapy [13]

Agric Econ 48:110 Le Martret B, Poage M, Shiel K, Nugent GD, Dix PJ (2011) Tobacco chloroplast transformants expressing genes encoding dehydroascorbate reductase, glutathione reductase, and glutathione-S-transferase, exhibit altered anti-oxidant metabolism and improved abiotic stress tolerance

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