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Adler Journal of Clinical Gastroenterology.2022

Neutrophil/lymphocyte ratio as a prognostic factor in biliary tract cancer. European journal of cancer (Oxford, England : 1990) vol

Additionally, it enhances the expression of aquaporin 5 and sodiumpotassium-chloride co-transporter 1 (NKCC1), leading to reduced inflammation and improved saliva flow rate [167]

Therefore, cancer cells adapt to this environment by altering glucose metabolization, with high rates of glucose uptake and glycolysis, as well as changes in glutamine synthesis, which are essential factors in the growth and metastasis of tumors (183)