Berberine also restored protein phosphate 2A (PP2A) activity and glycogen synthase kinase 3 (GSK-3) activity (GSK-3 Tyr216 and Ser9 site phosphorylation increased) (Yu et al., 2011)

2.4 Blood biochemical analysis This study assessed 52 biomarkers as the clinical features: albumin (ALB), globulin (GLB), albumin/globulin (ALB/GLB), alanine transaminase (ALT), aspartate transaminase (AST), aspartate transaminase/alanine transaminase (AST/ALT), serum gamma-glutamyl transferase (GGT), alpha fetoprotein (AFP), carcinoembryonic antigen (CEA), creatinine (Cre), urine acid (UA), fasting blood glucose (Glu), serum total cholesterol (TC), TG, high-density lipoprotein cholesterol (HDLC), nonhigh-density lipoprotein cholesterol (non HDLC), low-density lipoprotein cholesterol (LDLC), serum total bile acid (TBA), TSH, C-reactive protein (CRP), anti-cyclic peptide containing citrulline (anti-CCP), EpsteinBarr virus nuclear antigen immunoglobulin A (NA IgA), EpsteinBarr virus viral capsid antigen immunoglobulin A (VCA IgA), procalcitonin (PCT), functional thyroid 3 (FT3), free triiodothyronine (FT3), free thyroxine (FT4), total protein (TP), urea, estimated glomerular filtration rate (eGFR), interleukin-27 (IL27), RBC, WBC count, Hb, HCT, MCV, MCH, MCHC, platelet (PLT), neutrophil (NEUT), percentage of neutrophils (NEUT%), lymphocyte (LYM), percentage of lymphocyte (LYM%), monocyte (MONO), percentage of monocyte (MONO%), eosinophil (EOSIN), percentage of eosinophil (EOSIN%), basophil (BASO), percentage of basophil (BASO%), Meam platelet volume (MPV), RDW and platelet distribution width (PDW)

Nathan et al., 2023
Maget A, Dalkner N, Hamm C, Bengesser SA, Fellendorf FT, Platzer M, et al