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PDHA1 alleviates myocardial ischemia-reperfusion injury by improving myocardial insulin resistance during cardiopulmonary bypass surgery in rats

Preliminary results from a study conducted with pregnant beef cows in late gestation reported increased maternal plasma MET concentrations in cows fed RPM and lower concentrations in those supplemented with GAA, with intermediate values in cows receiving both RPM + GAA (Motta et al., 2025), highlighting the role of GAA as a methyl consumer

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Current research is focused on targeting inflammasomes, glial signaling, and regulated cell death as strategies to mitigate neurodegeneration [156]