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Although conventional or reduced-dose HMAs exhibit some activity in patients with LR-MDS, the limited activity and transient response of HMAs following the failure of ESAs as first-line therapy means they are seldom used [258]

Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging

ACS Chem Biol 2010

A selective ACAT-1 inhibitor, K-604, stimulates collagen production in cultured smooth muscle cells and alters plaque phenotype in apolipoprotein E-knockout mice