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Indeed, nitrated aSyn is almost exclusively found in the insoluble protein fraction making aSyn more resistant to degradation, more compact, and more stable 112,113

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For example, it is not inconceivable that eventually micro- or nano-fluidic technology and other future technologies will deliver the lab-on-a-chip that Theranos recently scandalously failed to deliver ( It is also hoped there will also be improvements in functional biomarkers to assess both folate and vitamin B12 status ( Along similar lines, the future may bring increased interest in assessing the extent to which people are exposed to excess folic acid

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