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Interestingly, MitoQ decreased H 2 O 2 after 2 hours of treatment, but this effect was reversed after 24 hours ( Figure 8B )

This suggests that amino acid metabolism is sensitive to specific changes of the TCA cycle and that regulation of amino acid metabolism is adjusted according to this specific change

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Others have been added, including exportin-1 (XPO1) inhibitors, signaling lymphocyte activation molecule family 7 (SLAMF7) antibodies, chimeric antigen receptor (CAR) T-cell therapies, and bispecific antibodies, which all may afford the opportunity to improve outcomes for patients with relapsed/refractory multiple myeloma