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Individuals at risk of vitamin B12 deficiency include older adults, people with gastrointestinal disorders, those who have had gastrointestinal surgeries, individuals on a strict vegan diet, individuals who take metformin for blood sugar control, and people taking proton pump inhibitors for chronic heartburn

Durability Efficacy against symptomatic infection also waned over time for all vaccines (average decrease of 13.6% per month, 95% CI 5.522.3 [5]