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Because these animals still develop glaucoma in response to elevated IOP, neither ECM plates nor the lamina cribrosa are likely to be necessary for pressure-induced axonal loss

Some patients with severe chronic schizophrenia exhibit cognitive deficits resembling bvFTD in both pattern and severity, particularly among inpatients (185)

For most women, the clinical conversation ends at oral contraceptives for cycle regulation, metformin for insulin resistance, and the diffuse instruction to "lose weight." What it rarely includes is any serious engagement with the signaling dysfunctions that make PCOS resistant to those blunt interventions in the first place