melanotic bowel movement Melanosis coli: a contrast effect or an oncogenic effect? A large-scale retrospective cohort study | International Journal of Colorectal Disease Melanosis Coli | Digestive Disease

Neuronal electrical activity induces ROS production attributed to both cytoplasmic and mitochondrial sources 24,25

Insulin IR-A receptor binding IGF-1 LR3 also binds the insulin receptor, preferentially the IR-A isoform (expressed in fetal cells, cancer tissues, central nervous system), with 10 to 100 fold lower affinity than for IGF-1R

In a phase 3 study, L-glutamine demonstrated a 25% reduction in the median number of pain crisis, 30% less hospitalizations and reduced acute chest episodes in children and adults with SCD with or without HU over a 48-week period

Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma