glutathione persister cells

glutathione persister cells cancer cells: Iron addiction and vulnerability to ferroptosis: Molecular Cell Drug-tolerant persister cancer cells are

Name: glutathione persister cells cancer cells: Iron addiction and vulnerability to ferroptosis: Molecular Cell Drug-tolerant persister cancer cells are
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Drug tolerant persister cancer cells are vulnerable to GPX4 inhibition PMC Sustained dysregulation of iron and glutathione homeostasis induces chronoferroptosis, a persistent ferroptotic adaptation in neuronal cells Cell Death Discovery Ferroptosis DOJINDO LABORATORIES Real Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function: Stem Cell Reports

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in addition, a mutual cis competition was found in the mitochondrial transport of 2-oxoglutarate and GSH (26)

143 While some of these agents have demonstrated isolated positive findings, the overall evidence base remains insufficient, with most studies being limited by small sample sizes, methodological variability, or lack of replication