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Each finding is rated by severity Red for immediate enforcement risk, Yellow for significant gray zone exposure, Green for lower priority with specific fix recommendations for each issue

This section summarizes the current crosssectional profile of PD stratified by age, sex, and region, reviews temporal trends over the past five decades, and discusses persistent knowledge gaps and future research priorities, with particular attention to underserved and underrepresented populations

Neutrophils may transfer miRNA-223 to liver macrophages, hepatocytes, and HSCs through extracellular vesicles during both active disease progression and resolution

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis