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On one hand, CBD stimulates sphingomyelinase and consequently, by enhancing sphingomyelin (SGM) cleavage, rises ceramides levels, reinforcing the structure of the epidermis and preserving skin moisture (Luczaj et al

Uma V, Kanthimathi M, Weyhermuller T, Nair BU (2005) Oxidative DNA cleavage mediated by a new copper (II) terpyridine complex: crystal structure and DNA binding studies

Small studies suggest improvements in sleep (18) (32) (34) , but effects on anxiety are mixed (17) (32)

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