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Macrophages play an important role in inflammatory events and promote the transcription of pro-inflammatory mediators

10.1074/jbc.M111988200 75 DedioJ.KonigP.WohlfartP.SchroederC.KummerW.Muller-EsterlW

Such pain is commonly associated with kidney problems, such as kidney stones or infections, given the kidneys' position against the back

SCFAs constitutes a direct linkage between gut microbiome and immune system due to their capability for inducting regulatory T-cells (Treg) [72] and regulating Tregs and Th17 balance [73]