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an overview

Both peptides should be sourced with a Certificate of Analysis (CoA) confirming HPLC purity of 98%+ for research-grade material

MOTS-c Primary focus: Mitochondrial metabolism Insulin sensitivity Metabolic aging in women MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is encoded in mitochondrial DNA not the nuclear genome and functions as a mitochondrial-derived peptide that communicates metabolic stress signals systemically

Seiwerth and colleagues (Inflammopharmacology, 1999) documented effects on angiogenic growth factor pathway signalling, and subsequent work has expanded characterisation to include VEGF receptor 2 upregulation, endothelial cell migration in capillary-formation assays, and improved healing in ischemia-reperfusion preparations