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The weight loss was accompanied by statistically significant improvements versus placebo on secondary endpoints, including waist circumference, blood glucose, blood pressure, and lipids, said Novo Nordisk, which also said UBT521 was safe and well-tolerated with a profile "consistent with incretin-based therapies." Novo Nordisk recently initiated an international phase 1b/2a trial of the triple G agonist, and the company is expecting to report results from that study next year