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Comparison of myo-inositol and metformin on glycemic control, lipid profiles, and gene expression related to insulin and lipid metabolism in women with polycystic ovary syndrome: a randomized controlled clinical trial

2.2.2 Mechanisms linking increased Hcy levels to MetS Elevated Hcy levels exert inhibitory effects on the insulin signaling pathway, primarily by inducing IR through the cysteine-homocysteinylation of the pro-insulin receptor

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The overall outcome includes an increase in healthy follicles, restoration of normal hormone levels, and normalization of the estrous cycle (Shareghi-Oskoue et al