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Altogether, these findings indicate that the TRPM2-mediated calcium influx pathway in microglia, particularly enhanced in reactive cells, has opened new research opportunities, suggesting that modulating TRPM2 activity could represent a strategy to regulate microglial function

Furthermore, it examines the most recent research discoveries concerning the diagnosis of EAOC and emphasizes potential targets for therapeutic intervention

a suitable subject or patient in need of therapy are identified by, for example, a health care professional or professionals using known tests, measurements or criteria