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Mechanism of trypsin-induced endothelium-dependent vasorelaxation in the porcine coronary artery

Serving as a ROS supergenerator, the prepared PMIC-NC could induce Type-I/II ROS generation through electron/energy transfer upon 660 nm laser irradiation as well as trigger endogenous burst of Type I ROS assisted by proton transients in tumor cells

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These metabolites are excreted primarily through urine and bile, with bioavailability depending on the administration route