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doi: 10.1089/ars.2006.8.1597

In vitro anti-Trypanosoma cruzi activity enhancement of curcumin by its monoketone tetramethoxy analog diveratralacetone

Health Technol Assess (Winchester, England)

446 The druggability properties are typically determined by the drugs requirements, necessitating that the lead compound be chemically facile to synthesize and possess desirable ADME (absorption, distribution, metabolism, excretion) characteristics