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The study participants were hypertensive (clinic systolic/diastolic BP of 140-179/90-109 mmHg and 24-hour ambulatory systolic/diastolic BP 130/80 mmHg) patients enrolled in a randomized controlled trial and treated with amlodipine 510 mg or nifedipine gastrointestinal therapeutic system (GITS) 3060 mg once daily

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This preparation could significantly enhance the immune activity of normal lymphocytes, 193 and it could induce cell cycle arrest or apoptosis in human prostate cancer cells 194 and in a mouse model bearing human multiple myeloma