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This indicates that NO and NaOCl may target similar specific thiols in mycobacteria that functions in the protection against ROS and RNS to ensure cellular survival and virulence under infection conditions

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To overcome these research bottlenecks, future studies should conduct more systematic in vivo experiments to simulate the complex physiological microenvironment, while designing more rigorous experimental protocols to elucidate the precise mechanisms by which TCM target the Wnt/-catenin signaling pathway in CRC treatment

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