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Description

Ji et al., 2019

G., Lin, T

In a concentration range compatible with the nocturnal surge (pM to nM), melatonin orchestrates a plethora of physiological functions by activating GPCRs receptors (MT1 and MT2) localized in plasmatic, nuclei and mitochondrial membranes

The first, an affinity-based probe named p-H4K16laAlk, allows for the UV-induced covalent capture of transiently interacting proteins directly from cell lysates