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Alzhaimers disease Alzhaimers disease (AD) is a chronic neurodegenerative disease characterized by the pathological accumulation of -amyloid peptides and neurofibrillary tangles into the brain, that usually starts slowly and gets worse over time up to dementia

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An inadequate or excessive compensatory adaptive response, termed malacclimatization, can impair oxygen delivery, leading to hypoxemia, which is defined as a decrease in the arterial partial pressure of oxygen (PaO)

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