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First, the simulation model containing the activating center (~400 atoms) of TYR was constructed (Supplementary Fig

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In addition, even though taking into account potential confounders is more important than the sample size by itself as aforementioned, our sample size may have limited the power to detect differences in patient-centered outcomes, particularly endoscopic remission. Several strengths have to be underlined such as the inclusion of consecutive patients with daily practice standardized evaluation and high-quality collected data anticipating the future use for real-world evidence research and methodological expertise in comparing real-world data [7,9,25]

A recent endoscopy shows a gastric ulcer with active bleeding