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[27] describe several requirements that biodegradable scaffolds must have: injectability, shear-thinning and self-healing, biocompatibility, low cytotoxicity, non-immunogenicity, non-mutagenicity, and promotion of cell proliferation, migration, and differentiation

R747W is a mutant phenotype with loss-of-function of the gene encoding iPLA2, which reduces the hydrolytic activity of 15-HpETE-PE, and increases the content of 15-HpETE-PE in cells, and increases the sensitivity to ferroptosis compared with the wild type

Thus, the ATP depletion and mitochondrial ROS burst observed upon SLC25A39 knockdown are expected to blunt PI3K/AKT signaling and subsequently inhibit mTORC1, driving the observed cell death

Spectra data were log-transformed and weighted by an adaptive intensity weighting algorithm