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Nasal route is generally lower-risk for such issues but care must still be taken with formulation, preservation, and absorption variability

This includes removal of wet clothing, raise patients room temperature, and cover with warm blankets

Therapeutics that block RSL3-mediated GPX4 inactivation may provide a targeted approach to preserving antioxidant capacity in ARDS patients, reducing the extent of ferroptosis-driven lung damage ( 5.3 Iron chelators Iron overload exacerbates ferroptosis by fueling ROS production and lipid peroxidation, making iron chelation a viable therapeutic approach

Both can be administered intranasally or subcutaneously and the reconstitution approach differs by route