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Autophagic deficits in PD are also found in immune cells, which is particularly relevant because microglia are the predominant cell type responsible for clearing aggregated -synuclein in the CNS [142]

Insufficient Folic Acid (Vitamin B9) is particularly concerning for pregnant women as it increases the risk of birth defects , such as spina bifida , in the developing foetus

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Adipocytes and bone marrow stromal cells in the TME can promote the resistance of tumor cells to ASNase treatment by supplying Gln and cysteine to leukemia cells, 348,349 and cancer-associated fibroblasts can secrete Asp to promote solid tumor growth