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Following Figure 4)

Therefore, the modern medicine and TCM have told us that the liver has extensive physiological and pathological relationships with other extrahepatic organs or tissues, and vice versa

Beyond its antioxidant capacity, this molecule is a heavy hitter in the livers detoxification pathways

As do other arsenicals, it induces G 2 /M cell cycle arrest and triggers apoptosis through disruption of mitochondrial functions and JNK activation and is responsible for reactive oxygen species production ( FIGURE 4 Darinaparsin was characterized in vitro as a potent inducer of growth arrest and apoptosis in a range of hematologic malignancies such as acute promyelocytic leukemia (APL), acute lymphoblastic leukemia, B cell lymphoma, and multiple myeloma (Matulis et al., 2009)